Coarse-grained simulations of stretching entangled DNA using oscillating electric fields.

نویسندگان

  • Richard S Graham
  • Ronald G Larson
چکیده

DNA stretching in entangling media with oscillating electric fields is useful in DNA sequencing. We propose that stretching occurs around hairpin loops at the chain ends, caused by interactions with the medium. Brownian dynamics simulations show that this mechanism explains several experimental observations, including a resonance with varying field frequency.

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عنوان ژورنال:
  • Chemical communications

دوره 47 1  شماره 

صفحات  -

تاریخ انتشار 2011